You won’t need the giant can of Pabst Blue Ribbon to laugh yourself sick at a Lady Business show, but go ahead and buy one. It’s classy. The ladies doing the business at the Comedy Spot downtown last night were seriously funny. Having never been to an improv show, or any comedy show for that matter, I wasn’t sure what to expect, but these gals delivered with energy and giggles to spare.

Taking subject matter from the audience, the girls had the whole audience rolling, portraying everything from insecure rats to competitive cats to a disenchanted witch-turned-esthetician. Lady Business was the perfect warm up for the following shows, Anti-Cooperation League and the always-sold-out Drunk vs. High. The latter pitches the two teams of various states of inebriation against each other in a sort of goofy extemporization battle, then allows the similarly mentally compromised audience to vote on a winner.

“It’s different here than in New York," Mignon Shrueder said. "There, things are very competitive, intense. Here everyone feels like family and is very supportive.”

Shrueder (picture a younger, blonder Laura Silverman) told me that while most of the comedians have normal day jobs and obligations, the Comedy Spot is a viable jumping-off point toward a successful career, some even moving on to Comedy Central. Brittany Birrer and Becca Costello agreed. These girls genuinely like each other, they are doing this because it’s fun, and it comes through in the performance.

Mel Gelbart consistently had the whole audience in stitches with what I can only describe as a “Molly Ringwald on crack” persona. Her caricature of a delusional girl with an imaginary boyfriend was straight up hilarious. She bounces from maniacal to dead pan like a child with ADD and no Ritalin in sight.

Don’t disregard the boys, though. After Lady Business, the men killed it in Anti-Cooperation League and Drunk vs. High.

Lady Business was a blast, and it wasn’t all about tampons and menstruation as my husband feared, so bring your man friends too. Tell them there are large cans of beer involved.